NovoMix 50 Flexpen

Manufacturer: Novo Nordisk

Pharmaceutical name: Insulin Aspart

Pack: 1 pack (5 pens x 3ml (100 iu/ml))

Active Ingredients: 50% Insulin Aspart / 50% Insulin Aspart Protamine

 

NovoMix 50 Flexpen is indicated for the management of diabetes and is suitable for individuals aged 10 years and older. 

 

NovoMix 50 Flexpen is administered via injection into the subcutaneous tissue of the abdominal wall (stomach) or thigh. It may also be injected subcutaneously in the deltoid (upper arm) or gluteal (buttock) areas if preferred. Regular monitoring of the patient’s blood glucose levels is essential to determine the optimal effective dose. NovoMix 50 Flexpen should be injected just before meals, although it may be administered after a meal if needed. Typical dosing ranges from 0.5 to 1.0 U per kilogram of body weight daily.

 

In cases of type 2 diabetes, NovoMix 50 Flexpen may be used alone or in conjunction with metformin (another antidiabetic medication). It can also be combined with other oral antidiabetic agents, but should only be used with pioglitazone after assessment of the patient’s risk for fluid-related side effects by a doctor.

 

Diabetes is a condition characterized by insufficient insulin production in the body to regulate blood glucose levels effectively. NovoMix 50 Flexpen serves as a substitute for insulin that closely resembles the insulin naturally produced by the pancreas.

 

The key component in NovoMix 50 Flexpen, insulin aspart, is generated using a technique called "recombinant DNA technology," whereby a yeast is modified to incorporate a gene (DNA) that enables it to synthesize insulin aspart.

 

Insulin aspart has a slight modification compared to human insulin, which allows it to be absorbed more quickly by the body, leading to a faster onset of action. NovoMix 50 Flexpen contains insulin aspart in two formulations: a soluble form that acts within 10 minutes of injection and a crystallized form that is absorbed more gradually throughout the day. This replacement insulin functions similarly to naturally produced insulin, facilitating the entry of glucose into cells from the bloodstream and thereby alleviating the symptoms and complications associated with diabetes.